{"id":1799,"date":"2026-04-30T13:17:22","date_gmt":"2026-04-30T13:17:22","guid":{"rendered":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/element-biosciences-cloudbreak-flow-cells-enable-any-application-scale\/"},"modified":"2026-04-30T13:17:24","modified_gmt":"2026-04-30T13:17:24","slug":"element-biosciences-cloudbreak-flow-cells-enable-any-application-scale","status":"publish","type":"post","link":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/element-biosciences-cloudbreak-flow-cells-enable-any-application-scale\/","title":{"rendered":"Element Biosciences: Cloudbreak\u2122 Flow Cells Enable Any\n                                Application at Any\n                                Scale"},"content":{"rendered":"<figure class=\"project-feature\"> <img decoding=\"async\" alt=\"Sciencewerke\" src=\"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-content\/uploads\/2026\/04\/WhatsApp%20Image1234567.webp\" style=\"padding-bottom: 20px;width: 70%;\"\/> <\/figure>\n<p class=\"text-justify\">Scale sample batching, extend read length, or run targeted panels.<\/p>\n<p class=\"text-justify\">Avidity base chemistry <b style=\"font-weight: bold;\">(ABC) brings a radically different solution to next-generation<br \/>\nsequencing (NGS). Unique to Element Biosciences, ABC innovates each step of<br \/>\nsequencing chemistry, separating base detection from strand extension to<br \/>\noptimize enzyme conditions for each step to deliver unsurpassed accuracy by<br \/>\nensuring ultrapure base-calling signals while reducing costly reagent<br \/>\nconsumption. It also generates scarless, natural DNA<\/b> that confers superior<br \/>\nperformance over many cycles of sequencing.<\/p>\n<p class=\"text-justify\">The<b style=\"font-weight: bold;\"> flexibility of selecting from several flow cell configurations based on<br \/>\n\t\t\t\t   readlength and throughput needs,<\/b> allows you the option of running 2&#215;75, 2&#215;150,<br \/>\n\t\t\t\t   or 2&#215;300 runs ranging <b style=\"font-weight: bold;\">from 100M reads<\/b> using the 2&#215;300 medium flow cell to <b>1B<br \/>\n\t\t\t\t   reads<\/b> from the 2&#215;150 or 2&#215;75 flow cells and sequencing kits.<\/p>\n<figure class=\"project-feature\"> <img decoding=\"async\" alt=\"Sciencewerke\" src=\"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-content\/uploads\/2026\/04\/WhatsApp%20Image123456.webp\" style=\"padding-bottom: 20px;width: 70%;\"\/> <\/figure>\n<p class=\"text-justify\">This table illustrates AVITI\u2019s added ability to leverage the high throughput flow cells<br \/>\nfor each of the three readlength options.<\/p>\n<p class=\"text-justify\">Cloudbreak is the latest advancement to avidity base chemistry (ABC), <b style=\"font-weight: bold;\">scaling to<br \/>\n\t\t\t\t\tsuit any experiment and enhancing operational efficiency <\/b>in multiple ways:<\/p>\n<ul style=\"list-style-type: disc;\">\n<li>\n<p>Increase sequencing speed with <b style=\"font-weight: bold;\">20% faster run times reduce 2 x 150 run times to &lt; 40 hours <\/b>and single cell experiments in less than a day.<\/p>\n<\/li>\n<li>\n<p>Load a linear library for automatic circularization onboard AVITI.<\/p>\n<\/li>\n<li>\n<p>Sequence and demultiplex Index 1 and Index 2 before Read 1 and Read 2 for<br \/>\n\t\t\t\t\t\t<b style=\"font-weight: bold;\"> real-time quality control and performance feedback.<\/b><\/p>\n<\/li>\n<li>\n<p><b style=\"font-weight: bold;\">Improve data quality <\/b>through the end of each read to enhance accuracy.<\/p>\n<\/li>\n<li>\n<p>Improve sequencing performance through difficult homopolymer regions.<\/p>\n<\/li>\n<\/ul>\n<figure class=\"project-feature\"> <img decoding=\"async\" alt=\"Sciencewerke\" src=\"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-content\/uploads\/2026\/04\/WhatsApp%20Image12345.webp\" style=\"padding-bottom: 20px;width: 70%;\"\/> <\/figure>\n<p class=\"\" style=\"font-size: 18px;\">Figure 2. ABC maintains high read quality after crossing a homopolymer at position<br \/>\n0, demonstrating an unaffected error rate versus SBS\u2019s five-fold increase (left). This<br \/>\nexceptional performance extends across most long polymers (&gt; 11 bp) in the human<br \/>\ngenome (right).*<\/p>\n<p class=\"\" style=\"font-size: 18px;\"><a href=\"https:\/\/www.sciencewerke.com\/aviti-system\" style=\"color:#178fcf;\"> Click here<\/a> to learn more about how AVITI\u2122 with Cloudbreak is the perfect sequencing<br \/>\nsolution for you:<\/p>\n<ul style=\"list-style-type: disc;\">\n<li>\n<p><a href=\"https:\/\/youtu.be\/cWr4m7fCnzc?si=R8x64wuMEhD35AkL\n\t\t\t\t\" style=\"color:#178fcf;\">\u201cAvidity Sequencing \u2013 Accuracy and Applications\u201d<\/a> <\/p>\n<\/li>\n<li>\n<p><a href=\"https:\/\/youtu.be\/4BxezHdgZSg?si=nex8ckEMtfMvXOVc\" style=\"color:#178fcf;\">\u201cDriving Exceptional Performance in NGS: Cloudbreak\u2122 Chemistry\u201d<\/a><\/p>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Scale sample batching, extend read length, or run targeted panels. Avidity base chemistry (ABC) brings a radically different solution to next-generation sequencing (NGS). Unique to Element Biosciences, ABC innovates each step of sequencing chemistry, separating base detection from strand extension to optimize enzyme conditions for each step to deliver unsurpassed accuracy by ensuring ultrapure base-calling [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[164],"tags":[],"class_list":["post-1799","post","type-post","status-publish","format-standard","hentry","category-164"],"_links":{"self":[{"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/posts\/1799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/comments?post=1799"}],"version-history":[{"count":2,"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/posts\/1799\/revisions"}],"predecessor-version":[{"id":2654,"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/posts\/1799\/revisions\/2654"}],"wp:attachment":[{"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/media?parent=1799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/categories?post=1799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pm11.corsivalab.xyz\/sciencewerke\/wp-json\/wp\/v2\/tags?post=1799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}