Introduction

Using Nuclera’s eProtein DiscoveryTM system, scientists can evaluate expression screens of 24 constructs with customizable cell-free blends in parallel. The construct that gives the highest yield can be selected for an off-cartridge protein purification scale up, delivering microgram quantities of purified protein in-hand in less than 48 hours. Nuclera’s technology integrates cell-free protein synthesis (CFPS) and digital microfluidics on eProtein Discovery Cartridges, allowing rapid progress on protein projects through a benchtop, automated, high throughput protein access system.

 

Protein Discovery Workflow

Streamline your path to protein-in-hand with 3 simple steps:

  • Step 1: Design and prepare DNA constructs
  • Step 2: Automated protein expression and purification screen on cartridge
  • Step 3: Scale up on the bench

 

Explore multiple expression combinations in parallel, on one instrument