Introduction

3D Bioprinting is a promising approach for personalized tissue engineering, but the lack of mechanical durability and biological relevance of bioprinted constructs has limited their clinical viability. 3DBioFibR’s patented dry-spinning technology produces μCollaFibR™; 50 μm collagen fibers that increase the shape fidelity and biological relevance of bioprinted constructs. With excellent chemical stability and 1-2 μm diameters, μCollaFibR™ is universally compatible with bioprinting materials and modalities.

    • Produced using GMP type I collagen, and resembles the structure of natural collagen fibers
    • Can be resuspended in any aqueous environment, including acidic environments (pH≥2)
    • Increases mechanical strength and modulus of hydrogels in extension and compression
    • Improves shape retention/durability for at least 28 days in cellular constructs
    • Acts as a physiologically relevant site for cell attachment within the constructs, improving cellular viability and functionality
    • Improves shape fidelity without compromising bioink viscosity/printability

Product Video

Mechanical Performance

Compression: 5%., GelMA with 1.25 mg/mL CollaFibR™

Extension: 7.5%., GelMA with 2.5 mg/mL CollaFibR™

 

 

Description

 

Product Specification

 

Collagen Bovine Type I
Length 44 ± 13 μm
Diameter 1 − 2 μm
**Stability in Solution ≥ 3 months at pH 2 − 7.4
Temperature Stability ≤ 60 oC
Hydrated Young’s Modulus 50 ± 16 kPa
Storage 4 oC short term, 20 oC long term
Degrading Enzyme Collagenase I/IV

 

 

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