Introduction

Nuvia HP-Q is a high-performance strong anion exchange resin. It is the latest product in the Nuvia family of high-capacity ion exchange resins and can be used for downstream purification of large molecules such as high molecular weight (HMW) plasma proteins IgA and IgM, viruses, VLPs, and PEGylated proteins.

The stability of this base bead and its broad chemical compatibility allows repeated uses with a long resin lifetime. Nuvia HP-Q particle size is designed to offer high dynamic binding capacity (DBC) at fast flow rates without excessive backpressure, thereby delivering excellent process economics. Its pore size is optimized for easy accessibility and adsorption of large biomolecules, and the internal spacer length and ligand density facilitate efficient binding of the biomolecules even at high flow rates.

Description

Features and Benefits

 Ideal for purification of large biomolecules
 Excellent pressure flow properties
 Recover more target biomolecule with less resin
 Increase productivity and decrease cycle time with high flow rates
 Easily scalable to meet manufacturing demands
 Improve overall process economics

Large Molecule Applications

 Plasma proteins IgA and IgM
 Viruses
 VLPs
 PEGylated proteins