BioReady nanoparticles are optimized for binding biomolecules to the nanoparticle surface. The nanoparticle conjugates are used in rapid diagnostic testing and sensing applications such as lateral flow immunoassays. To make a reporter particle selection follow these guidelines:
For the highest sensitivity in rapid diagnostic tests use 150 nm carboxyl gold nanoshells for covalent binding to proteins.
If you just need the increased stability, reduced antibody costs, higher sample matrix stability, and more reproducible conjugates provided by covalent binding chemistry use 40 nm or 80 nm carboxyl gold nanoparticles.
If you are looking for increased sensitivity for passive conjugates, try our “bare” carbonate nanoparticles.